Real Madrid boss Zinedine Zidane hopes to have Gareth Bale and James Rodriguez fit and available after the international break.
Muscle problems will keep both players out of Saturday's LaLiga game against Eibar despite them being called up to their respective national teams.
Wales winger Bale has not played a minute since a Euro 2020 qualifier close to a month ago, while midfielder James has missed Madrid's past three matches.
The pair have started individual fitness programmes but will not be considered for selection until they are able to complete full training sessions alongside the rest of the first team.
"They haven't been fit enough to play," Zidane said at Friday's pre-match news conference.
"If they're going to go [away on international duty], they're going to go. They've got five or six days to see if they're fit enough to play for their country. They're not fit enough to play on Saturday.
"They haven't trained with the team. They've been training a little but not at the same pace as their team-mates. If players aren't training with their team-mates they can't play.
"They're not injured right now."
Bale's injury occurred in the same international fixture that left Croatia midfielder Luka Modric with bruising to his right quadriceps.
The 34-year-old subsequently sat out two club games, leaving Zidane wary of a repeat as his squad prepares to disassemble.
"Hopefully nothing happens, but it could. It's true in the last call-ups the players got injured," he said.
"Hopefully the players get away with the national teams, they play, and there are no injuries, and everyone comes back fit and available."
Amid the probe over why Bale and James have been absent, Zidane was asked to clarify his recent claim that Kylian Mbappe harbours a "dream" of playing for Madrid.
The Los Blancos boss said that he was simply repeating the Paris Saint-Germain star's own acknowledged ambition.
The comment riled PSG sporting director Leonardo, who called for an end to transfer speculation surrounding Mbappe.
Zidane said: "He's within his rights to have his opinion and when I get asked a question I will also say what I believe.
"All I said was what [the player] said, that Mbappe's dream is to one day wear the Real Madrid shirt. There's not really much to it to be honest."