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Dr. Edwin Jenner (Noah Emmerich)

Season 1, “TS-19”
The last surviving employee of the Center for Disease Control after the apocalypse began, kind, well-intentioned Jenner worked until there was nothing more he could do to try to reverse things. He offered Rick and his group food and shelter, and a chance to die peacefully with him inside the about-to-detonate CDC headquarters. When they decided to flee and take their chances in the new world, Jenner dropped this bombshell in Rick’s ear: Everyone carries the disease that will turn them into a walker when they die, whether they’ve been bitten by a walker or not. (Photo: AMC)

'The Walking Dead': 16 memorable 1-episode characters

Kimberly Potts
Writer, Yahoo Entertainment

To celebrate the Oct. 22 Season 8 premiere of  The Walking Dead — the series’ 100th episode — Yahoo Entertainment will be posting a new TWD-related story every day through the season opener.

With a deep bench of talent like the cast of The Walking Dead, it’s no small feat to make an impression with just one appearance. But that’s exactly what these TWD characters did, leaving us thinking about them seasons after, in some cases, they stole a scene. From the last real scientist (sorry, Eugene) the survivors meet to the endearing woman who’s smart enough to be afraid of a damn tiger, here are 16 characters who made a lasting impression with just the briefest amount of screen time.

The Walking Dead Season 8 premieres Oct. 22 at 9 p.m. on AMC.