The French midfielder has missed the last four matches but could start against the Canaries.
Striker Harry Kane (hamstring), midfielder Moussa Sissoko (knee), left-back Ben Davies (ankle) and goalkeeper Hugo Lloris (elbow) are out.
Norwich defender Ben Godfrey will miss the trip to the Tottenham Hotspur Stadium as he begins a three-match ban.
Godfrey was sent off during the Canaries’ 1-0 win over Bournemouth on Saturday after referee Paul Tierney upgraded from a yellow card to a red after reviewing his challenge on striker Callum Wilson on the pitchside monitor.
Emiliano Buendia is out with a thigh problem and fellow midfielder Mario Vrancic is nursing a shin injury, while back-up keeper Ralf Fahrmann (knee) is also sidelined.
Tottenham provisional squad: Gazzaniga, Vorm, Walker-Peters, Aurier, Tanganga, Alderweireld, Vertonghen, Sanchez, Rose, Sessegnon, Winks, Dier, Ndombele, Gedson, Alli, Moura, Son, Eriksen, Lamela, Lo Celso.
Norwich provisional squad: Krul, McGovern, Aarons, Zimmermann, Byram, Tettey, Duda, Cantwell, Pukki, McLean, Hanley, Lewis, Amadou, Hernandez, Leitner, Trybull, Drmic.