The Europa League group phase starts on Thursday evening and Jose Mourinho will be hoping to take his side all the way in a competition he has already won twice before.
Mourinho lifted the UEFA Cup, as it was then known, with FC Porto before winning the Europa League with Manchester United in 2017 - now he’s hoping to take Tottenham to glory too.
First up for Spurs in the groups is Austrian side LASK Linz, who have won two of their four games this season domestically.
Also in Group J are Belgian side Antwerp and Bulgarian outfit Ludogorets.
Here’s everything you need to know ahead of the match.
When is the match?
The game kicks off at 8pm on Thursday, 22 October.
Where can I watch it?
The match will be shown live on BT Sport 2. Subscribers can also stream the match via the BT Sport website or app.
What is the team news?
Spurs are likely to line-up with Hugo Lloris in goal, while at full-back, it is likely to be Matt Doherty and Ben Davies replacing Serge Aurier and Reguilon. The centre-backs will probably not see any changes as Davinson Sanchez and Toby Alderweireld were impressive against West Ham and will want to continue that form.
Dele Alli will be hoping to be included in midfield having started in all of the Europa League qualifiers so far. Gareth Bale could expect to start but do not be surprised if Jose Mourinho names a much-changed side.
Erik Lamela is also expected to feature in some capacity, while there’s a decision to make up front as Harry Kane has been in exceptional form, but Carlos Vinicius is waiting for his full debut.
LASK will be without midfielder Dominik Reiter, who has a torn cruciate ligament. Outside of that, the Austrian side will be able to call upon a full-strength squad which they will need against Tottenham who are by far the superior team.
Tottenham: Lloris, Doherty, Alderweireld, Sanchez, Davies, Winks, Hojbjerg, Bale, Alli, Lamela, Kane.
LASK: Lawal, Ramsebner, Filipovic, Weisinger, Ranftl, Holland, Michori, Renner, Gruber, Balic, Raguz.
Spurs’ squad strength should be far too much for LASK to handle even if there is plenty of rotation and subs on the night. Spurs 4-0 LASK