Scientists have discovered that testing the levels of certain proteins in blood samples can predict whether a person at risk of psychosis is likely to develop a psychotic disorder years later. The study, published in the current edition of JAMA Psychiatry, was led by researchers from RCSI University of Medicine and Health Sciences. Many of these proteins are involved in inflammation, suggesting that there are early changes in the immune system in people who go on to develop a psychotic disorder. The findings also suggest that it is possible to predict their outcomes using blood samples taken several years in advance. A patent application has been filed, and the research team is working to commercialise this research through licensing or partnering with industry.