People who have had major sinus surgery should consult their ENT doctor before undergoing the COVID-19 swab testing, a new research suggested. The findings of the study were published in the journal 'JAMA Otolaryngology - Head and Neck Surgery'. Issues include incorrect angling of the swab and inappropriate depth of insertion. If the swab angle is too high, a puncture may occur. The sinuses can protect the skull base to a degree, said Dr Chen. Injury from incorrect nasopharyngeal swab technique, while rare, may include cerebrospinal fluid leakage or severe bleeding. Polymerase chain reaction via nasopharyngeal swabs is a test frequently used to detect SARS-CoV-2 infection.