Erik Lamela could win his first Argentina cap in more than two years after winning a recall for November's twin friendlies against Mexico.
Tottenham winger Lamela, plagued by injuries over recent seasons, has enjoyed a strong start to the current campaign, scoring five goals in as many competitive appearances.
That form could see the 26-year-old make his first international appearance since the World Cup qualifying draw with Venezuela in September 2016.
Lamela’s Spurs teammate Juan Foyth is also part of the squad, with Manchester United’s Sergio Romero, Manchester City’s Nicolas Otamendi and Watford’s Roberto Pereyra completing the Premier League representation in Lionel Scaloni's latest squad.
Former Juventus midfielder Pereyra makes the squad for the second consecutive time, having made his national team comeback during the October international break and scoring on his return against Iraq.
The Hornets star has been in excellent form at club level with five goals in 10 appearances for Javi Gracia's side this season, including two in his last pair of appearances.
Club America goalkeeper Agustin Marchesin and Zenit defender Emanuel Mammana also return to Scaloni's 30-strong group, while 20-year-old Matias Zaracho is the only new face.
The Racing Club midfielder has featured regularly for Argentina's league leaders in his third season as a professional.
Lionel Messi, Sergio Aguero, Angel Di Maria and Gonzalo Higuain, none of whom have featured since the World Cup in Russia, all remain absent.
Argentina will host Mexico in Cordoba on November 16 and then in Mendoza four days later.
Argentina squad in full:
Augustin Marchesin (Club America), Sergio Romero (Manchester United), Geronimo Rulli (Real Sociedad); Juan Foyth (Tottenham), Ramiro Funes Mori (Villarreal), Walter Kannemann (Gremio), Emanuel Mammana (Zenit), Gabriel Mercado (Sevilla), Nicolas Otamendi (Manchester City), German Pezzella (Fiorentina), Renzo Saravia (Racing Club), Nicolas Tagliafico (Ajax); Marcos Acuna (Sporting CP), Santiago Ascacibar (Stuttgart), Rodrigo Battaglia (Sporting CP), Franco Cervi (Benfica), Rodrigo De Paul (Udinese), Erik Lamela (Tottenham), Giovani Lo Celso (Real Betis), Maximiliano Meza (Independiente), Leandro Paredes (Zenit), Roberto Pereyra (Watford), Eduardo Salvio (Benfica), Franco Vazquez (Sevilla), Matias Zaracho (Racing Club); Angel Correa (Atletico Madrid), Paulo Dybala (Juventus), Mauro Icardi (Inter), Lautaro Martinez (Inter), Giovanni Simeone (Fiorentina).