Mourinho's side face Royal Antwerp in the Europa League on Thursday and the plan for a limited number of socially-distanced supporters to be in the stadium was abandoned by Belgian authorities at the weekend, amid a surge in infections.
Spurs will remain in a bio-secure bubble for the duration of the tip and Mourinho believes European away days are safer than international football, where players come together from a number of different clubs, and insisted the world cannot stop entirely due to the virus.
"I prefer myself, if that is the case [that cases are rising] to take a few risks, but very controlled risks," Mourinho said.
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"But play football and do my job and give people what they love, which is football, and if people can’t come to the stadium they have us at home and I just want to think positively about it. We try to be safe as we can in the club."
"In the clubs, the situation is much more controlled," he added. "Nobody is free from problem. But the bubble exists and we try as much to be protected.
"I believe that national teams are the space where even with great organisation lots of travelling and players travelling separately is more dangerous.
"But at a club level what we did, for example, today leaving the training ground all together after being controlled twice, arriving here, going direct to the hotel, staying in the hotel and not leaving, coming here tomorrow. The area in the dressing room is beautiful, clean, new, safe. Honestly I feel safe."
"Maybe something wrong happens with myself. We finish the game and go home and in our case we don’t go home, we go to the training ground and we stay there to prepare for the game on Sunday.
"We try to do our lives. The world can not stop. Football is an important area so I am more than ready to keep doing what we are doing."