The Guinean champions are wounded as they were beaten 2-0 by Tunisian giants Esperance de Tunis away in their previous Group B match last weekend.
The result saw Horoya remain second on the group standings with seven points from five games, while Esperance have already booked their place in quarter-finals as group winners with an unassailable 11 points.
|Horoya vs. Orlando Pirates|
|Date||Saturday, March 16|
TV Channel, Live Score & How To Watch
The match will be live on SS4. You can also catch live updates on Goal.com .
|Live Match Centre||TV Channel|
Squads & Team News
HAC are heading into their clash with the Buccaneers looking to avoid a defeat in order to secure their place in the knockout stages as Group B runners-up.
French coach Patrice Neveu will be banking on Ocansey Mandela's scoring form with the Ghanaian attacker having scored in HAC's two home matches against Esperance and FC Platinum.
The 1978 Caf Cup Winners' Cup champions are currently enjoying a 14-match unbeaten run at home in the Champions League having drawn 2-2 with Pirates' PSL rivals Mamelodi Sundowns in Conakry last year.
Meanwhile, Pirates were frustrated by a resilient Zimbabwean side Platinum at home in their previous Group B match which ended in a 2-2 draw last weekend.
The draw saw the Buccaneers remain third on the group standings - a point behind second-placed Horoya setting up an intriguing clash between the two teams on the final day of the group stage.
Only a win in Guinea will see Pirates join Esperance in the quarter-finals as Group B runners-up, while a draw or defeat would eliminate the Soweto giants from the tournament.
Serbian trainer Milutin 'Micho' Sredojevic will look to Thembinkosi Lorch, who will be brimming with confidence after being named PSL Player of the Month for March 2019.
The 1995 Champions League will be hoping to improve their away record in the Champions League having recorded four defeats, two draws and two wins.
This will be the second meeting between Horoya and Pirates.
Pirates secured a 3-0 victory over Horoya at the Orlando Stadium on Group B matchday two.