George McEachran, Conor Gallagher and Jamie Cumming are among the youngsters who are travelling to Hungary for Chelsea's Europa League match against MOL Vidi, Goal understands.
Manager Maurizio Sarri could name the trio on the bench for the encounter in Budapest, despite none of them having yet made their professional debuts for the club.
Sarri is set to ring the changes for the Blues' final Europa League group-stage match with one eye on the Premier League clash with Brighton at the weekend.
Callum Hudson-Odoi and Ethan Ampadu could both start the game, with Sarri mindful of a hectic festive fixture list and the need to rotate.
Hudson-Odoi scored and laid on an assist as the Blues beat PAOK Salonika 4-0 in their last outing in the competition, while Ampadu played 27 minutes as a substitute in that game.
Chelsea will be without the injured Mateo Kovacic after he was substituted in the second half of the Blues' 2-0 win over Manchester City, which ended the Premier League champions’ unbeaten run. It is understood that he sustained a thigh muscle strain.
The striker was dropped from the squad for the victory over City, with Eden Hazard playing in a false nine role and Olivier Giroud named as a substitute.
He has scored twice in three games in the Europa League, netting against both Vidi and PAOK, and has netted a total of seven strikes in 20 appearances across all competitions.
Chelsea fly to Hungary on Wednesday, having already secured top spot in Group L. The Blues have won five games out of five, and have scored 10 goals, conceding just one.
Danny Drinkwater and Lucas Piazon both trained with the first-team ahead of the Europa League game, but neither are eligible to play in the game having not been registered for the competition.
Chelsea face Vidi, Brighton, Bournemouth, Leicester, Watford and Crystal Palace before the turn of the year, prior to games against Southampton, Newcastle, Arsenal and Bournemouth in January.
They will also face Nottingham Forest in the third round of the FA Cup on January 5.