Spurs are now just a single point behind Frank Lampard’s side, while both teams are being forced to contend with separate attacking injury crises.
Chelsea suffered a miserable defeat against Manchester United last Monday as Lampard was once again left to rue his side’s toothlessness in attack.
Jose Mourinho’s side, however, despite a less than impressive performance against Aston Villa, were saved by a last-gasp Son Heung-min winner, before their unbeaten streak was ended by RB Leipzig in midweek.
Here is everything you need to know:
When is it and what time is kick-off?
The match will begin at 12.30pm on Saturday 22
What TV channel is it on?
The match will be broadcast live on BT Sport 1, with coverage beginning at midday.
What is the team news?
Chelsea: Callum Hudson-Odoi, Christian Pulisic and N’Golo Kante have all been ruled out, with the latter suffering a groin injury against Manchester United. However, Tammy Abraham could return to the starting line-up after recovering from an ankle injury. Ruben Loftus-Cheek is still regaining match fitness after a long layoff.
Tottenham: Moussa Sissoko, Harry Kane and Son-Heung are all out, with the latter undergoing elbow surgery earlier this week, leaving Mourinho with little choice but to start one of Lucas Moura and Dele Alli as an unconventional striker.
Chelsea: Caballero, Azpilicueta, Christensen, Rudiger, James, Jorginho, Kovacic, Alonso, Barkley, Mount, Giroud
Tottenham Hotspur: Lloris, Sanchez, Alderweireld, Vertonghen, Tanganga, Ndombele, Winks, Lo Celso, Davies, Lucas Moura, Bergwijn