Jorginho is suspended, Ross Barkley not yet fit after injury and Mason Mount could miss the game with an ankle issue, though Frank Lampard has been boosted by the return of N'Golo Kante this week.
Crystal Palace and Roy Hodgson will be targeting another impressive away performance and have the chance to go fifth should they secure three points.
However Palace have not won in three Premier League games, and meet a Chelsea side in excellent goalscoring form and high on confidence.
Here is everything you need to know about the game.
Frank Lampard will be without the supsended Jorginho and Ross Barkley, who is still working his way back from injury, while Mason Mount will be assessed before the game and could miss out. Reece James is pressing for a start, while N’Golo Kante is set to make a return to the starting lineup after his own injury issues.
Conversely, Andros Townsend, Gary Cahill and Cheikou Kouyate are all likely to be available for selection for Crystal Palace, which means Roy Hodgson has a fully fit squad to choose from. Mamadou Sakho may have to be content with a place among the substitutes as he returns from injury.
Chelsea: Arrizabalaga, James, Tomori, Zouma, Emerson Palmieri, Kante, Kovacic, Willian, Mount, Pulisic, Abraham
Crystal Palace: Guaita, Ward, Tomkins, Cahill, van Aanholt, Townsend, Kouyate, Milivojevic, McArthur, Zaha, Ayew
Crystal Palace 8/1
Crystal Palace have proved tricky opponents this season, and will be confident they can take something from Stamford Bridge, particularly with Chelsea’s injury issues.
Yet Frank Lamapard’s men have been in fine fettle, and thus our prediction is 3-1 to Chelsea.
When is it?
Kick-off at Stamford Bridge is at 12.30pm GMT on November 9.
How can I watch it?
The match will be shown live on BT Sport 1, with coverage beginning at 12pm.
BT Sport customers can watch the game via the BT Sport app, or via the online player.