Roy Hodgson‘s side have already beaten Manchester United and held Arsenal away from home this season, and they meet a Chelsea side with selection issues in midfield.
Frank Lampard could be without Mason Mount in addition to Jorginho (suspended) and Ross Barkley (injured), which means the return of N’Golo Kante is a timely one.
Hodgson, on the other hand, has a fully fit squad from which to choose, including fit-again Mamadou Sakho, though the centre-half may start on the bench.
Here is everything you need to know about the game.
When is it?
Kick-off at Stamford Bridge is at 12.30pm GMT on November 9.
How can I watch it?
The match will be shown live on BT Sport 1, with coverage beginning at 12pm.
BT Sport customers can watch the game via the BT Sport app, or via the online player.
Frank Lampard will be without the supsended Jorginho and Ross Barkley, who is still working his way back from injury, while Mason Mount will be assessed before the game and could miss out. Reece James is pressing for a start, while N’Golo Kante is set to make a return to the starting lineup after his own injury issues.
Conversely, Andros Townsend, Gary Cahill and Cheikou Kouyate are all likely to be available for selection for Crystal Palace, which means Roy Hodgson has a fully fit squad to choose from. Mamadou Sakho may have to be content with a place among the substitutes as he returns from injury.
Chelsea: Kepa; Reece James, Kurt Zouma, Fikayo Tomori, Cesar Azpiliceuta; N’Golo Kante, Billy Gilmour, Mateo Kovacic; Willian, Tammy Abraham, Christian Pulisic.
Crystal Palace: Vicente Guaita, Joel Ward, Gary Cahill, James Tomkins, Patrick van Aanholt; Luka Milivojevic, Cheikhou Kouyate, James McArthur; Andros Townsend, Wilfried Zaha, Jordan Ayew.
Crystal Palace 8/1
Crystal Palace have proved tricky opponents this season, and will be confident they can take something from Stamford Bridge, particularly with Chelsea’s injury issues.
Yet Frank Lamapard’s men have been in fine fettle, and thus our prediction is 3-1 to Chelsea.