Denver Broncos star Emmanuel Sanders will miss the remainder of the NFL season with a torn Achilles.
The Broncos were dealt the major blow on Wednesday after wide receiver Sanders went down during practice midweek.
Sanders was helped off the field and did not put any weight on his left leg as he was taken into the locker room for further evaluation, according to reports.
The injury happened early in practice as he went down during passing drills. Sanders slipped when he was making a cut on a short route.
Denver claimed former Buffalo Bills receiver Andre Holmes off waivers
Sanders has made a significant impact this season for the Broncos' offense as he has 71 receptions, almost twice as many as his nearest team-mate, for a team-high 868 yards and four touchdowns through 12 games.
The Broncos (6-6) have climbed back into the AFC playoff discussion with a three-game winning streak that they put on the line against the 49ers in San Francisco on Sunday.