The French forward was a late substitute in the 2-2 draw at Celta Vigo on Saturday as Ansu Fati started and was warned by coach Quique Setien afterwards that his price tag will count for little.
But the 29-year-old looks likely to feature alongside Lionel Messi and Luis Suarez in this one as Barca fight to stay in the race for the title.
In midfield, Sergio Busquets is available again after suspension and will start, possibly alongside Ivan Rakitic and Arturo Vidal.
Youngster Riqui Puig is another alternative after his impressive display at Balaidos, but Arthur Melo is unlikely to start after his summer transfer to Juventus was announced on Monday.
Sergi Roberto is back after a rib fracture and could come in at right-back, but Frenkie de Jong is still out with a calf problem and Ousmane Dembele is ineligible in LaLiga after he was deregistered following a serious injury in February to allow Martin Braithwaite to be signed from Leganes in an emergency transfer.
Atletico have seen their appeal against Koke’s suspension turned down, so the midfielder will play no part in this match at Camp Nou.
Centre-back Stefan Savic is also banned, while defenders Sime Vrsaljko and Mario Hermoso are sidelined.
Barcelona are two points behind leaders Real Madrid with six rounds remaining, while Atletico are in third, four ahead of Sevilla in fourth and six clear of Getafe in fifth.
Barcelona predicted XI: Ter Stegen; Semedo, Pique, Lenglet, Alba; Vidal, Busquets, Rakitic; Messi, Suarez, Griezmann
Atletico predicted XI: Oblak; Arias, Gimenez, Felipe, Lodi; Thomas, Saul; Joao Felix, Llorente, Lemar; Costa